Transcranial Doppler Combined With Quantitative Electroencephalography Brain Function Monitoring for Estimating the Prognosis of Patients With Posterior Circulation Cerebral Infarction

Posterior circulation cerebral infarction (PCCI) can lead to deceased infratentorial blood flow (CBF) and metabolism. Neural activity is closely related regional both spatially temporally. Transcranial Doppler (TCD) combined with quantitative electroencephalography (QEEG) a technique that evaluates neurovascular coupling involves synergy between the metabolic vascular systems. This study aimed monitor brain function using TCD-QEEG estimate efficacy of for predicting prognosis patients PCCI. We used recording system perform monitoring; we recorded clinical variables simultaneously. The data were analyzed Cox proportional hazards regression model. Receiver-operating characteristic (ROC) curve analysis was evaluate cut-off diastolic velocity (VD) (delta + theta)/(alpha beta) ratio (DTABR). area under ROC (AUROC) calculated assess predictive validity variables. Forty (aged 63.7 ± 9.9 years; 30 men) assessed. Mortality at 90 days 40%. TCD indicators VD [hazard (HR) 0.168, confidence interval (CI) 0.047–0.597, p = 0.006] QEEG DTABR (HR 12.527, CI 1.637–95.846, 0.015) independent predictors outcomes. AUROC after combination 0.896 showed better accuracy than Glasgow Coma Scale score (0.75), (0.76), (0.781; all < 0.05). provides good understanding mechanisms in improve our ability predict